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Journal of the National Cancer Institute Advance Access published online on June 22, 2009
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djp158
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© The Author 2009. Published by Oxford University Press.

CORRESPONDENCE

Re: Insulin, Insulin-like Growth Factor-I, and Risk of Breast Cancer in Postmenopausal Women

Riccardo Vigneri, Francesco Frasca, Laura Sciacca, Paolo Vigneri, Lucia Frittitta

Affiliations of authors: Endocrinology Division, Department of Internal and Specialistic Medicine, Garibaldi-Nesima Hospital and University of Catania, Catania, Italy (RV, FF, LS, LF); General Pathology Section, Department of Biomedical Sciences, University of Catania, Catania, Italy (PV)

Correspondence to: Riccardo Vigneri, MD, Divisione di Endocrinologia, Ospedale Garibaldi, Via Palermo 636, 95122 Catania, Italy (e-mail: vigneri@unict.it).

The first 10% of the full text of this article appears below.

Gunter et al. (1) reported results of a large prospective case–control study, confirming that hyperinsulinemia is an independent risk factor for postmenopausal breast cancer. They also discussed a variety of possible mechanisms for breast cancer promotion by hyperinsulinemia and concluded that lowering insulin levels may be a possible strategy . . . [Full Text of this Article]


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