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Journal of the National Cancer Institute Advance Access published online on February 26, 2008
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djn039
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© The Author 2008. Published by Oxford University Press.

EDITORIALS

Clinically Relevant Standards for Intensity-Modulated Radiation Therapy Dose Prescription

John Willins, Lisa Kachnic

Affiliations of authors: Department of Radiation Oncology, Boston Medical Center, Boston, MA (JW, LK) and Department of Radiation Oncology, Massachusetts General Hospital, Boston MA (JW, LK)

Correspondence to: John Willins, PhD, Department of Radiation Oncology, Boston Medical Center, Moakley Building, Ste LL100, 830 Harrison Ave, Boston, MA 02118 (e-mail: john.willins@bmc.org).

The first 150 words of the full text of this article appear below.

Intensity-modulated radiation therapy (IMRT) offers definite advantages over traditional three-dimensional (3D) treatment methods but at the expense of increased complexity, to say nothing of increased labor. Clinicians involved with multicenter clinical trials have learned that both IMRT and 3D treatment plans can be difficult to compare among institutions because of varying physician preferences in defining the tumor bed and nodal volumes on which the radiation is targeted (1,2). However, with 3D treatment planning, we can expect, at least, that methods of radiation dose prescription, calculation, and reporting are reasonably unambiguous if investigators follow a common framework for target definition and prescription, such as Report 50 of the International Commission on Radiation Units (3), and for dose determination, such as the Task Group 51 report of the American Association of Physicists in Medicine (4). With IMRT planning, this expectation is much less certain . . . [Full Text of this Article]


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Correspondence about this Article

Re: Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems
Arthur Olch and Robert Lavey
J Natl Cancer Inst 2008 100: 1263. [Extract] [Full Text] [PDF]

Re: Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems
James Deye, James Purdy, and Bhadrasain Vikram
J Natl Cancer Inst 2008 100: 1263-1264. [Extract] [Full Text] [PDF]

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This article has been cited by other articles:


Home page
 JNCI J Natl Cancer InstHome page
A. Olch and R. Lavey
Re: Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems
J Natl Cancer Inst, September 3, 2008; 100(17): 1263 - 1263.
[Full Text] [PDF]

Home page
 JNCI J Natl Cancer InstHome page
J. Willins and L. Kachnic
Response: Re: Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems
J Natl Cancer Inst, September 3, 2008; 100(17): 1266 - 1267.
[Full Text] [PDF]

Home page
 JNCI J Natl Cancer InstHome page
J. Deye, J. Purdy, and B. Vikram
Re: Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems
J Natl Cancer Inst, September 3, 2008; 100(17): 1263 - 1264.
[Full Text] [PDF]