Skip Navigation



Journal of the National Cancer Institute Advance Access published online on November 13, 2007
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djm227
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
99/22/1654    most recent
djm227v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Sporn, M. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sporn, M. B.
Related Collections
Right arrowRelated Articles in JNCI
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2007. Published by Oxford University Press.

EDITORIALS

A New Tumor Suppressor Gene, Selective for Lung Cancer

Michael B. Sporn

Affiliation of author: Dartmouth Medical School, Remsen, Hanover, NH

Correspondence to: Michael B. Sporn, MD, Dartmouth Medical School, 7650 Remsen, Hanover, NH 03755 (e-mail: michael.b.sporn@dartmouth.edu).

The first 10% of the full text of this article appears below.

The search for genes that modulate susceptibility to carcinogenesis continues to be an active and important area of research. Several years ago, Cheng and Lotan cloned a novel human gene, designated as "retinoic acid-inducible gene 1" (RAIG1) (1). The deduced RAIG1 protein sequence contained seven transmembrane domains, characteristic of G protein–coupled receptors. The ligand for this putative receptor was not identified at the time, and, indeed, this remains the case, although there has been continuing interest in RAIG1 (subsequently renamed "G protein–coupled receptor family C group 5 member A," . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related Articles in JNCI

Identification of the Retinoic Acid–Inducible Gprc5a As a New Lung Tumor Suppressor Gene
Qingguo Tao, Junya Fujimoto, Taoyan Men, Xiaofeng Ye, Jiong Deng, Ludovic Lacroix, John L. Clifford, Li Mao, Carolyn S. Van Pelt, J. Jack Lee, Dafna Lotan, and Reuben Lotan
J Natl Cancer Inst 2007 99: 1668-1682. [Abstract] [Full Text] [PDF]

IN THIS ISSUE
J Natl Cancer Inst 2007 99: 1653. [Extract] [Full Text] [PDF]