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Journal of the National Cancer Institute Advance Access published online on October 9, 2007
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djm179
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© The Author 2007. Published by Oxford University Press.

EDITORIALS

Competing Risks for Patients With Localized Prostate Cancer

Jerome Seidenfeld, David J. Samson, Peter C. Albertsen

Affiliations of authors: Technology Evaluation Center, Blue Cross and Blue Shield Association, Chicago, IL (JS, DJS); Division of Urology, University of Connecticut Health Center, Farmington, CT (PCA)

Correspondence to: Jerome Seidenfeld, PhD, Technology Evaluation Center, Blue Cross and Blue Shield Association, 225 North Michigan Ave, Chicago, IL 60601 (e-mail: jerome.seidenfeld@bcbsa.com).

The first 10% of the full text of this article appears below.

In health care, as in the rest of life, decisions have consequences. A chosen treatment for prostate cancer can yield benefits, but it can also cause harm. In localized prostate cancer, as in most diseases, baseline characteristics influence the natural history of the disease and thus a treatment's potential for benefit. The most relevant estimates for an individual come from studies involving patients who are similar to the individual selecting treatment.

The recently updated guideline from the American Urological Association lists the following primary treatments for localized prostate cancer: watchful waiting, active surveillance, interstitial brachytherapy, external beam radiotherapy, radical prostatectomy, primary hormonal therapy, and others (e.g., cryotherapy) (1). To choose from this menu, patients . . . [Full Text of this Article]


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