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Journal of the National Cancer Institute Advance Access published online on September 11, 2007

JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djm162
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© Oxford University Press 2007.

NEWS

Soy and Prostate Cancer Study Results Mixed

Brian Vastag

The first 10% of the full text of this article appears below.

In 1985, Herman Adlercreutz, M.D., and colleagues at the University of Helsinki discovered high levels of estrogen-like soy compounds in the urine of Japanese men. Given the low rate of prostate cancer among Japanese men and the anti–prostate cancer effects of estrogens, Adlercreutz hypothesized that high soy consumption protected against the disease.

More than two decades later, scientists are still trying to confirm the idea.

"It's been a long road," said Adlercreutz, who has published dozens of reports examining the two main soy phytoestrogens, daidzein and genistein—classified as isoflavones—and their effect on cancer development.

The latest study examining the issue, a large prospective report from Japan . . . [Full Text of this Article]

Gut Bacteria May Be Key to Soy Benefit


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