Skip Navigation



Journal of the National Cancer Institute Advance Access published online on August 28, 2007
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djm146
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
99/17/1288    most recent
djm146v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Beckman, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beckman, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© Oxford University Press 2007.

NEWS

Pregnancy Problem Yields Insight Into Cancer Drug–Induced High Blood Pressure

Mary Beckman

The first 10% of the full text of this article appears below.

Blood vessel growth, or angiogenesis, is a popular target in cancer therapies these days. After all, cancers need blood to grow, so cutting off their supply can choke them to death. Three approved, effective drugs all inhibit the same key molecule that simulates angiogenesis, but they all seem to have a similar side effect: high blood pressure.

No one is sure how these drugs cause high blood pressure, but research in renal cancer and a pregnancy complication called preeclampsia offers one intriguing hypothesis. Women with preeclampsia have dangerously high blood pressure, and renal cancer biologist Vikas Sukhatme, M.D., Ph.D., at Beth Israel Deaconess Medical Center in Boston suggests that the cancer drugs cause high blood pressure in the same way that it does in some pregnant . . . [Full Text of this Article]

Hypertension Risk Factor

Clamping Down on VEGF

Getting Along


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?