Journal of the National Cancer Institute Advance Access published online on July 10, 2007
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djm039
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© The Author 2007. Published by Oxford University Press.
CORRESPONDENCE |
Re: Pregnancies, Breastfeeding, and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study (IBCCS)
Affiliations of authors: Department of Genetic Oncology, INSERM UMR599, Institut Paoli-Calmettes, Marseille, France (LH); Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, PQ, Canada (MPS)
Correspondence to: Laetitia Huiart, MD, MSc, MPH, Department of Genetic Oncology, Institut Paoli-Calmettes, INSERM UMR599, 232 Blvd Sainte Marguerite BP 156, 13273 Marseille Cedex 9, France (e-mail: huiartl@marseille.fnclcc.fr).
| The first 10% of the full text of this article appears below. |
Andrieu et al. (1) recently reported on the association between pregnancies and breast cancer risk in a large cohort of 1601 BRCA1/2 mutation carriers. They showed that later age at first full-term pregnancy was associated with a reduction in the risk of breast cancer for BRCA1 mutation carriers. This issue is important because it may affect the type of family planning counseling that young women receive.
The decreasing trend between later age at pregnancy and breast cancer risk reported by Andrieu et al. can either
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