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Unstable Leukemia Stem Cells May Predispose Patients to Drug Resistance
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Journal of the National Cancer Institute
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The BCR-ABL gene in chronic myeloid leukemia stem cells has a tendency to quickly mutate, and this may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National
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J Natl Cancer Inst 2007 99: 662-663.
J Natl Cancer Inst 2007 99: 680-693.