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JNCI Journal of the National Cancer Institute 2007 99(4):331-332; doi:10.1093/jnci/djk056
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© The Author 2007. Published by Oxford University Press.

CORRESPONDENCE

Response: Re: A Model of Human Tumor Dormancy: An Angiogenic Escape From the Nonangiogenic Phenotype

George N. Naumov, Randolph S. Watnick, Nava Almog, Lars A. Akslen, Judah Folkman

Affiliation of authors: Department of Surgery, Vascular Biology Program, Children's Hospital and Harvard Medical School, Boston, MA (GNN, RSW, NA, JF); The Gade Institute, Section for Pathology, University of Bergen, Norway (LAA)

Correspondence to: Judah Folkman, MD, Karp Family Research Laboratories 12.128, 300 Longwood Ave, Boston, MA 02115 (e-mail: judah.folkman@childrens.harvard.edu).

The first 10% of the full text of this article appears below.

We appreciate the comments of Sardari Nia et al. It is well established in the literature that all expanding tumors need a supporting vasculature. Sardari Nia et al. contend that large tumors can grow by co-option, a process that was first described by Holash et al. (1), who demonstrated that tumor cells can grow as perivascular cuffs in thickness no more than the oxygen . . . [Full Text of this Article]


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Related Article in JNCI

Re: A Model of Human Tumor Dormancy: An Angiogenic Escape From the Nonangiogenic Phenotype
Peyman Sardari Nia, Eric Van Marck, and Paul Van Schil
J Natl Cancer Inst 2007 99: 331. [Extract] [Full Text] [PDF]