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JNCI Journal of the National Cancer Institute 2007 99(24):1821; doi:10.1093/jnci/djm281
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© Oxford University Press 2007.

IN THIS ISSUE

The first 10% of the full text of this article appears below.

Possible Tumor Suppressor and Aggressive Prostate Cancer Risk

The genetic factors that underlie the risk or progression of prostate cancer are largely unknown. In an exploratory study, Duggan et al. (p. 1836) analyzed 60,000 single-nucleotide polymorphisms (SNPs) for associations with a diagnosis of aggressive prostate cancer. The exploratory study identified seven candidate SNPs. Further testing in two cohorts—one composed of individuals of European descent and the other of African Americans—suggested that a possible tumor suppressor gene, DAB2IP, was in fact associated with an increased risk of aggressive prostate cancer.

In an editorial, . . . [Full Text of this Article]

Radiologist Characteristics and Diagnostic Mammograms

Extended Adjuvant Therapy for Postmenopausal Breast Cancer

Cancer Incidence Over Time in Blood Transfusion Recipients

Understanding Trends in Prostate Cancer Incidence and Mortality

Cancer Risk for Heterozygotes with the Founder NBN Mutation


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