Journal of the National Cancer Institute Advance Access originally published online on November 27, 2007
JNCI Journal of the National Cancer Institute 2007 99(23):1815-1816; doi:10.1093/jnci/djm210
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© The Author 2007. Published by Oxford University Press.
CORRESPONDENCE |
Re: Declines in Invasive Breast Cancer and Use of Postmenopausal Hormone Therapy in a Screening Mammography Population
Affiliations of author: Department of Surgery, University of Washington, Seattle, WA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA
Correspondence to: Benjamin O. Anderson, MD, Department of Surgery, Section of Surgical Oncology, Box 356410, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195 (e-mail: banderso@u.washington.edu).
| The first 10% of the full text of this article appears below. |
Kerlikowske et al. (1) suggest that decreased use of hormone replacement therapy (HRT) led to decreased breast cancer incidence in a mammographically screened study population. Using sophisticated modeling techniques, the authors were able to show statistical significance in changing HRT and breast cancer diagnosis rates. However, the clinical conclusions reached by the authors are poorly justified if not contradicted by their
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J Natl Cancer Inst 2007 99: 1816-1817.