© The Author 2007. Published by Oxford University Press.
CORRESPONDENCE |
Re: Extended Lung Cancer Incidence Follow-up in the Mayo Lung Project and Overdiagnosis
Affiliation of authors: Center for the Biology of Natural Systems, School of Earth and Environmental Sciences, Queens College, City University of New York, Flushing, NY
Correspondence to: Alfredo Morabia, MD, PhD, Center for the Biology of Natural Systems, School of Earth and Environmental Sciences, Queens College, City University of New York, 163-03 Horace Harding Expressway, Flushing, NY 11365 (e-mail: alfredo.morabia@qc.cuny.edu).
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Marcus et al. (1) are to be commended for successfully carrying out the follow-up of the 1983 survivors of the Mayo Lung Project. We question, however, whether overdiagnosis of screening-detected lung cancer is a necessary or sufficient explanation of the observed results.
If we assume that successful randomization resulted in two study arms with a similar risk of lung cancer throughout follow-up, the existence of
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J Natl Cancer Inst 2007 99: 899.