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JNCI Journal of the National Cancer Institute 2007 99(11):836; doi:10.1093/jnci/djk231
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© Oxford University Press 2007.

NEWS

Preliminary Breast Cancer Vaccine Study Shows Promise

Charles Bankhead

The first 10% of the full text of this article appears below.

A vaccine designed to treat breast cancer has performed surprisingly well in an initial clinical study.

In a phase II trial of 186 patients, the vaccine targeting the HER2/neu E75 peptide reduced the risk of recurrence by 50% in 101 breast cancer patients who were clinically disease free after treatment compared with those who were not treated with the vaccine. Immunized patients also had about a 20% improvement in disease-free survival, according to a presentation at the San Antonio Breast Cancer Symposium in December, though . . . [Full Text of this Article]

The Future of an E75 Vaccine


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