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JNCI Journal of the National Cancer Institute 2006 98(9):643-644; doi:10.1093/jnci/djj168
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© The Author 2006. Published by Oxford University Press.

CORRESPONDENCE

RESPONSE: Re: Tamoxifen for the Prevention of Breast Cancer: Current Status of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

Bernard Fisher, Joseph P. Costantino

Affiliations of authors: Department of Surgery (BF), Department of Biostatistics (JPC), University of Pittsburgh, Pittsburgh, PA; National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, PA (BF, JPC)

Correspondence to: Bernard Fisher, MD, 300 Halket St., Suite 350, Pittsburgh, PA 15213 (e-mail: fisherb2@upmc.edu).

The first 10% of the full text of this article appears below.

Cuzick et al. contend that it was inappropriate both to announce the results of the National Surgical Adjuvant Breast and Bowel Project (NSABP) prevention trial (P-1) (1,2) and to unblind the participants. They argue that those actions make it difficult to interpret the data from P-1 and that important information has been lost. We disagree.

We question some key points in . . . [Full Text of this Article]


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Related Correspondence

Re: Tamoxifen for the Prevention of Breast Cancer: Current Status of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
Jack Cuzick, John F. Forbes, and Anthony Howell
J Natl Cancer Inst 2006 98: 643. [Extract] [Full Text] [PDF]



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Y. Shen, J. P. Costantino, and J. Qin
Tamoxifen Chemoprevention Treatment and Time to First Diagnosis of Estrogen Receptor-Negative Breast Cancer
J Natl Cancer Inst, October 15, 2008; 100(20): 1448 - 1453.
[Abstract] [Full Text] [PDF]