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JNCI Journal of the National Cancer Institute 2006 98(5):363-364; doi:10.1093/jnci/djj075
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© The Author 2006. Published by Oxford University Press.

CORRESPONDENCE

RESPONSE: Re: Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers

Hisayuki Shigematsu, John D. Minna, Adi F. Gazdar

Affiliation of authors: Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas

Correspondence to: Adi F. Gazdar, MD, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Bldg. NB8-206, Dallas, TX 75390-8593 (e-mail: adi.gazdar@utsouthwestern.edu).

The first 10% of the full text of this article appears below.

We wish to comment on several points raised by Pardinas et al. concerning our findings regarding EGFR gene mutations in lung cancers (1). First, they suggest that two of the complex mutations we described, D8 and {Delta}9, may not be due to combinations of deletions or insertions and nucleotide substitutions as we indicated. . . . [Full Text of this Article]


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Related Correspondence

Re: Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers
Jose R. Pardinas, Li Xiao, Jia Zhang, and Kai Li
J Natl Cancer Inst 2006 98: 362-363. [Extract] [Full Text] [PDF]