© The Author 2006. Published by Oxford University Press.
EDITORIAL |
After the Deluge: The Emerging Landscape of Childbearing Potential in Pediatric Cancer Survivors
Correspondence to: Leslie R. Schover, PhD, Department of Behavioral Science, Unit 1330, The University of Texas M. D. Anderson Cancer Center, PO Box 301439, Houston, TX 77230-1439 (e-mail: lschover@mdanderson.org).
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A woman's ability to become pregnant, carry the pregnancy successfully, and give birth to a healthy child are all paradoxically threatened by many of the cancer treatments that enable girls to survive to adulthood. Like Hurricane Katrina, pediatric cancer is a tempest that leaves a concealing flood of acute treatment effects in its wake. Chronic problems only appear as the waters recede. Or perhaps the story of Noah's ark is a more apt metaphor of preserving fecundity for the new world that emerges after the deluge. Surveys of the large cohort of the Childhood Cancer Survival Study (CCSG), supplemented by clues from small, clinical