© 2005 Oxford University Press
CORRESPONDENCE |
RESPONSE: Re: Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer Agents
Affiliation of authors: Department of Blood and Marrow Transplantation, Section of Molecular Hematology and Therapy, The University of Texas M. D. Anderson Cancer Center, Houston
Correspondence to: Michael Andreeff, MD, PhD, Department of Blood and Marrow Transplantation, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Unit 448, Houston, TX 77030 (e-mail: mandreef@mdanderson.org).
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We appreciate the interest of Dr. Wolf and colleagues in our work. We understand their concerns related to the xenogenic nature of our model. However, we think that the data presented in their letter do not undermine the concept or conclusions presented in our article.
Wolf and colleagues used a syngeneic murine model (murine tumors, murine mesenchymal stem cells [MSC]) as
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J Natl Cancer Inst 2005 97: 540-541.