© 2005 Oxford University Press
CORRESPONDENCE |
RESPONSE: Re: Role of Detection Method in Predicting Breast Cancer Survival: Analysis of Randomized Screening Trials
Affiliation of authors: Department of Biostatistics and Applied Mathematics, M. D. Anderson Cancer Center, University of Texas, Houston, TX
Correspondence to: Donald A. Berry, PhD, Department of Biostatistics and Applied Mathematics, Unit 447, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030 (e-mail: dberry@mdanderson.org).
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We thank Paci et al. (1) for their correspondence. They suggest that we should have performed a survival analysis by intention to treat with or without adjustment for tumor characteristics. Intention-to-treat analyses are critical in assessing treatment (or screening) benefit in randomized trials. This assessment
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J Natl Cancer Inst 2005 97: 1853-1854.