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JNCI Journal of the National Cancer Institute 2005 97(14):1091-1092; doi:10.1093/jnci/dji191
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© 2005 Oxford University Press

CORRESPONDENCE

Re: Prognostic Significance of a Short Sequence Insertion in the MCL-1 Promoter in Chronic Lymphocytic Leukemia

Uta C. F. Nenning, Cornelia Eckert, Sven Wellmann, Andrea Barth, Günter Henze, Karl Seeger

Affiliation of authors: Department of Pediatric Oncology/Hematology, Charité Medical Center, Humboldt-University, Berlin, Germany

Correspondence to: Karl Seeger, MD, PhD, Department of Pediatric Oncology/Hematology, Charité Medical Center, Humboldt-University, Berlin, Germany (e-mail: karl.seeger@charite.de).

The first 10% of the full text of this article appears below.

Moshynska et al. (1) recently reported the finding of somatic nucleotide insertions in the promoter region of the antiapoptotic myeloid cell leukemia 1 (MCL-1) gene in patients with chronic lymphocytic leukemia (CLL), giving a possible explanation of the mechanisms responsible for higher MCL-1 expression in these patients. The authors showed that these mutations were of prognostic significance in that they were . . . [Full Text of this Article]


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Response to this Correspondence

RESPONSE: Re: Prognostic Significance of a Short Sequence Insertion in the MCL-1 Promoter in Chronic Lymphocytic Leukemia
Oksana Moshynska and Anurag Saxena
J Natl Cancer Inst 2005 97: 1093-1095. [Extract] [Full Text] [PDF]