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© 2005 Oxford University Press
CORRESPONDENCE |
Re: Association of a Common Variant of the CASP8 Gene With Reduced Risk of Breast Cancer
Affiliations of authors: Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany (BF, JLB, KH, BB); Department of Biosciences at Novum, Karolinska Institute, Huddinge, Sweden (KH); Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany (RK); Institute of Transfusion Medicine and Immunology, Red Cross Blood Service of Baden-Württemberg-Hessia, University of Heidelberg, Faculty of Clinical Medicine, Mannheim, Germany (PB); Division of Molecular Gynaeco-Oncology, Department of Gynaecology and Obstetrics, Clinical Center University of Cologne, Germany (BW, RKS)
Correspondence to: Bernd Frank, PhD, German Cancer Research Center (DKFZ), Division of Molecular Genetic Epidemiology, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany (e-mail: b.frank@dkfz.de).
| The first 10% of the full text of this article appears below. |
Recently, MacPherson et al. (1) reported an association between the common caspase-8 (CASP8) gene variant D302H and reduced breast cancer risk. They studied two independent U.K. cohorts from Sheffield and East Anglia and observed statistically significant lower frequencies of the CASP8 DH and HH genotypes in both case patient populations compared with the respective control
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J Natl Cancer Inst 2005 97: 1012-1013.
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