© 2005 Oxford University Press
CORRESPONDENCE |
RESPONSE: Re: Long-Term Efficacy of Zoledronic Acid for the Prevention of Skeletal Complications in Patients with Metastatic Hormone-Refractory Prostate Cancer
Correspondence to: Fred Saad, MD, Director of Urologic Oncology, Professor of Surgery Department of Surgery/Urology, Centre Hospitalier de l'Université de Montréal, Hôpital Notre-Dame, 1560 Rue Sherbrooke East, Montréal, PQ, Canada H2L 4M1 (e-mail: fred.saad@ssss.gouv.qc.ca)
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Dr. Tanvetyanon raised concerns about the long-term safety of zoledronic acid for the treatment of bone metastases in patients with hormone-refractory prostate cancer. These concerns must be viewed from the perspective of this patient population, in which the median survival is 15 to 18 months. This 24-month randomized, placebo-controlled, double-blind study offers the most stringent and objective assessment of the efficacy and
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J Natl Cancer Inst 2005 97: 70.