© 2005 Oxford University Press
CORRESPONDENCE |
Re: Long-Term Efficacy of Zoledronic Acid for the Prevention of Skeletal Complications in Patients with Metastatic Hormone-Refractory Prostate Cancer
Correspondence to: Tawee Tanvetyanon, MD, Loyola University Stritch School of Medicine, Cardinal Bernardin Cancer Institute, 2160 S. First Ave., Maywood, IL 60153 (e-mail: ttanve@lumc.edu)
| The first 10% of the full text of this article appears below. |
Serious concerns arose as I read the article by Saad et al. (1). First, the authors concluded that long-term treatment with zoledronic acid was safe. However, in my opinion, a 24-month follow-up for this potent bisphosphonate is not sufficiently long to make that conclusion. Longer use (i.e., >40 months) of another nitrogen-containing bisphosphonate, pamidronate, has been
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J Natl Cancer Inst 2005 97: 70-71.