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JNCI Journal of the National Cancer Institute 2004 96(7):556-557; doi:10.1093/jnci/djh092
© 2004 by Oxford University Press
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© 2004 Oxford University Press

CORRESPONDENCE

RESPONSE: Re: Playing the Old Piano: Another Tune for Endocrine Therapy

V. Craig Jordan, Clodia Osipo, Dong Cheng, Joan S. Lewis

Affiliation of authors: Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

Correspondence to: V. Craig Jordan, OBE, PhD, DSc, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 303 East Chicago Ave., Olson Pavilion Rm. 8258, Chicago, IL 60611 (e-mail: vcjordan@northwestern.edu)

The first 10% of the full text of this article appears below.

The estrogen receptor (ER) has proved to be an excellent target in breast cancer therapeutics (1); however, examination of the simple mathematics of response rates of ER-positive disease to endocrine therapy illustrates that about two-thirds of the patients ultimately benefit from successful target acquisition (Fig. 1). Nevertheless, endocrine therapy through the ER yields diminishing returns. Indeed, Koeberle et . . . [Full Text of this Article]


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Correspondence about this Article

RESPONSE: Re: Playing the Old Piano: Another Tune for Endocrine Therapy
Daniel F. Hayes
J Natl Cancer Inst 2004 96: 557. [Extract] [Full Text] [PDF]