© 2004 by Oxford University Press
© 2004 Oxford University Press
EDITORIAL |
Ductal Lavage for Early DetectionWhat Doesn't Come Out in the Wash
Affiliations of authors: Departments of Internal Medicine (CJF), Radiation Oncology (BFK), and Preventive Medicine and Public Health (MSM), University of Kansas Medical Center, Kansas City, KS
Correspondence to: Carol J. Fabian, MD, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160 (e-mail: cfabian@kumc.edu)
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Early detection via screening mammography has played a major role in the declining breast cancer mortality rates over the past decade (1,2). The impact of screening mammography on mortality rates is less for women younger than 50 years because of a lower test sensitivity and a lower rate of breast cancer (35). Sensitivity for detection of breast cancer in general screening populations has been reported as 61%81% for women aged 4049 years (5) and 87% for women aged 5064 years (6). The lower sensitivity is in turn attributed to higher breast density in younger women (7). Unfortunately, women at increased risk of breast cancer by virtue of having a family history of breast cancer, proliferative breast disease with or