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© 2004 Oxford University Press
CORRESPONDENCE |
Re: Cost-Effectiveness of Aspirin Chemoprevention for Barrett's Esophagus
Affiliations of authors: Digestive Diseases Centre, Departments of Genetics and Molecular Medicine, University of Leicester, Leicester, UK (JJ); GI Unit, McMaster University, Hamilton, Ontario, Canada (PM)
Correspondence to: J. A. Z. Jankowski, MD, PhD, FRCP, Level 4, Windsor Building, Departments of Genetics and Molecular Medicine, Medical School and University Hospitals Trust, Royal Infirmary, LE1 5WW, Leicester, UK (e-mail: j.jankowski@le.ac.uk)
| The first 10% of the full text of this article appears below. |
We write in regard to the article by Hur et al. (1) that appeared in the Journal. This article highlighted the value of aspirin for chemoprevention of Barrett's esophagus. We believe that this article is extremely timely. We are now addressing this same point in one of the largest randomized controlled trials in clinical gastroenterology that will involve 5000 male patients aged between 40 and 75 years with long-segment Barrett's metaplasia of the esophagus and have a 2-by-2 intervention trial factorial design (Fig. 1). This trial has been reviewed and funded by external grant authorities in the United Kingdom (namely Cancer Research
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J Natl Cancer Inst 2004 96: 887.
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