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JNCI Journal of the National Cancer Institute 2003 95(9):683-684; doi:10.1093/jnci/95.9.683-a
© 2003 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 95, No. 9, 683-684, May 7, 2003
© 2003 Oxford University Press

CORRESPONDENCE

Re: Trends in Use of Adjuvant Multi-Agent Chemotherapy and Tamoxifen for Breast Cancer in the United States: 1975–1999

V. Craig Jordan, Monica Morrow

Affiliations of authors: V. C. Jordan (Robert H. Lurie Comprehensive Cancer Center), M. Morrow (Department of Surgery, The Feinberg School of Medicine), Northwestern University, Chicago, IL.

Correspondence to: V. Craig Jordan, Ph.D., D.Sc., Northwestern University Medical School, Robert H. Lurie Comprehensive Cancer Center, 8258 Olson, 303 E. Chicago Ave., Chicago, IL 60611 (e-mail: vcjordan@nwu.edu).

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The finding of Mariotto et al. (1)—a decline in the use of adjuvant tamoxifen in lymph node-positive postmenopausal women since 1991—is of great interest. The authors suggest that the decline resulted from the recognition of an association between tamoxifen and endometrial cancer in this group of women. However, we suggest that the explanation is more complex. Tamoxifen is associated with only a modest increase . . . [Full Text of this Article]


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