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JNCI Journal of the National Cancer Institute 2003 95(23):1736-1737; doi:10.1093/jnci/djg130
© 2003 by Oxford University Press
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© 2003 Oxford University Press

EDITORIALS

Research and Public Health Implications of the Intricate Relationship Between Calcium and Vitamin D in the Prevention of Colorectal Neoplasia

Elizabeth T. Jacobs, María Elena Martínez, David S. Alberts

Affiliations of authors: Arizona Cancer Center (ETJ, MEM, DSA), College of Public Health (ETJ, MEM, DSA), Nutritional Sciences Interdisciplinary Program (MEM, DSA), and Department of Medicine (DSA), University of Arizona, Tucson.

Correspondence to: Elizabeth T. Jacobs, PhD, College of Public Health, Arizona Cancer Center, University of Arizona, P.O. Box 245024, Tucson, AZ 85724–5024 (e-mail: jacobse@u.arizona.edu)

The first 10% of the full text of this article appears below.

In this issue of the Journal, Grau et al. (1) present the results of a study investigating whether calcium supplementation, vitamin D, and vitamin D receptor (VDR) polymorphisms—alone or in combination—affect the risk of colorectal adenoma recurrence. This study provides the framework for consideration of issues related to the reported results, as well as to future cancer epidemiologic studies. These issues include 1) the need for further examination of the protective benefits of calcium and vitamin D on colorectal cancer and its precursors, 2) the necessity of and potential approaches for epidemiologic studies that address both genetic and environmental factors, and 3) the public health implications of . . . [Full Text of this Article]


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Correspondence about this Article

Research and Public Health Implications of the Intricate Relationship Between Calcium and Vitamin D in the Prevention of Colorectal Neoplasia
Robert P. Heaney
J Natl Cancer Inst 2004 96: 805-806. [Extract] [Full Text] [PDF]

RESPONSE: Re: Research and Public Health Implications of the Intricate Relationship Between Calcium and Vitamin D in the Prevention of Colorectal Neoplasia
Elizabeth T. Jacobs, María Elena Martínez, and David S. Alberts
J Natl Cancer Inst 2004 96: 806-807. [Extract] [Full Text] [PDF]



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