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JNCI Journal of the National Cancer Institute 2003 95(20):1555-1556; doi:10.1093/jnci/djg087
© 2003 by Oxford University Press
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© 2003 Oxford University Press

CORRESPONDENCE

Recurrent Episodes of Involuntary Masticatory Spasms Induced by Continuous Infusion of Oxaliplatin

Daniele Santini, Bruno Vincenzi, Annalisa La Cesa, Manuele Casale, Fabrizio Salvinelli, Giuseppe Tonini

Affiliations of authors: D. Santini, B. Vincenzi, A. La Cesa, G. Tonini (Oncology), M. Casale, F. Salvinelli (Otolaryngology), Campus Bio-Medico University, Rome, Italy.

Correspondence to: Daniele Santini, MD, Campus Bio-Medico University, Via Emilio Longoni, 83, 00155 Rome, Italy (e-mail: d.santini@unicampus.it).

The first 10% of the full text of this article appears below.

Oxaliplatin-containing regimens are now considered standard therapeutic options for patients with metastatic colorectal cancer (1). Oxaliplatin has a very good safety profile, and the dose-limiting toxicity of oxaliplatin is neurosensory toxicity (2). In approximately 90% of patients, oxaliplatin is associated with acute reversible neurotoxicity that is characterized . . . [Full Text of this Article]


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