© 2003 by Oxford University Press
© 2003 Oxford University Press
BRIEF COMMUNICATION |
Age at Immigration and Duration of Stay in Relation to Risk for Testicular Cancer Among Finnish Immigrants in Sweden
Affiliations of authors: A. Ekbom, Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital, Stockholm, Sweden, and Department of Epidemiology, Harvard School of Public Health, Boston, MA; L. Richiardi, O. Akre, P. Sparén, Department of Medical Epidemiology, Karolinska Institutet, Stockholm; S. M. Montgomery, Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital.
Correspondence to: Anders Ekbom, MD, PhD, Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital, M9:01, SE-171 76 Stockholm, Sweden (e-mail: Anders.Ekbom{at}medks.ki.se).
ABSTRACT
Although the incidence of testicular cancer is increasing, substantial differences in incidence between countries and populations exist. These differences cannot be explained solely by genetic differences, but environmental exposures, particularly early exposures, have been implicated in the etiology of testicular cancer. To assess whether early exposures contribute to the incidence of testicular cancer, we identified 93 172 Finnish men who immigrated to Sweden between 1969 and 1996 and followed them for the occurrence of testicular cancer. The risk of testicular cancer was lower for Finnish immigrants to Sweden than for the Swedish general population (standardized incidence ratio [SIR] = 0.34, 95% confidence interval [CI] = 0.21 to 0.53). The reduced risk was associated with both seminomas and non-seminomas. Neither age at immigration nor duration of stay in Sweden had any impact on the reduced risk. Although the type of environmental exposures remains unknown, the results strongly indicate that early exposures are major determinants for testicular cancer.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. Myrup, T. Westergaard, T. Schnack, A. Oudin, C. Ritz, J. Wohlfahrt, and M. Melbye Testicular Cancer Risk in First- and Second-Generation Immigrants to Denmark J Natl Cancer Inst, January 2, 2008; 100(1): 41 - 47. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. J. Genuis Health issues and the environment--an emerging paradigm for providers of obstetrical and gynaecological health care Hum. Reprod., September 1, 2006; 21(9): 2201 - 2208. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Rajpert-De Meyts Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects Hum. Reprod. Update, May 1, 2006; 12(3): 303 - 323. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Montgomery, F. Granath, A. Ehlin, P. Sparen, and A. Ekbom Germ-Cell Testicular Cancer in Offspring of Finnish Immigrants to Sweden Cancer Epidemiol. Biomarkers Prev., January 1, 2005; 14(1): 280 - 282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Richiardi, R. Bellocco, H.-O. Adami, A. Torrang, L. Barlow, T. Hakulinen, M. Rahu, A. Stengrevics, H. Storm, S. Tretli, et al. Testicular Cancer Incidence in Eight Northern European Countries: Secular and Recent Trends Cancer Epidemiol. Biomarkers Prev., December 1, 2004; 13(12): 2157 - 2166. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Bromen, A. Stang, C. Baumgardt-Elms, C. Stegmaier, W. Ahrens, K. A. Metz, and K.-H. Jockel Testicular, Other Genital, and Breast Cancers in First-Degree Relatives of Testicular Cancer Patients and Controls Cancer Epidemiol. Biomarkers Prev., August 1, 2004; 13(8): 1316 - 1324. [Abstract] [Full Text] [PDF]
|
|