© 2003 by Oxford University Press
Journal of the National Cancer Institute, Vol. 95, No. 12, 917,
June 18, 2003
© 2003 Oxford University Press
CORRESPONDENCE |
Re: Italian Randomized Trial Among Women With Hysterectomy: Tamoxifen and Hormone-Dependent Breast Cancer in High-Risk Women
Affiliations of authors: R. Narasimhadevara, Cancer Prevention Centre, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada; M. N. Pollak, Program in Cancer Prevention, McGill University, and Cancer Prevention Centre, Sir Mortimer B. Davis Jewish General Hospital; W. D. Foulkes, Program in Cancer Genetics, McGill University, and Cancer Prevention Centre, Sir Mortimer B. Davis Jewish General Hospital.
Correspondence to: William D. Foulkes, M.B. Ph.D., Cancer Prevention Centre Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste Catherine Road, Room C-107, Montreal, Quebec, Canada H3T 1E2 (e-mail: william.foulkes@mcgill.ca).
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Veronesi et al. (1) report findings from the large-scale Italian Randomized Trial of Tamoxifen. Their results show that the risk-reducing effects of tamoxifen on high-risk women with breast cancer are most marked for estrogen receptor (ER)-positive tumors. Women at high risk were defined as being