© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 7, 533,
April 3, 2002
© 2002 Oxford University Press
CORRESPONDENCE |
RESPONSE: Re: Night Shift Work, Light at Night, and Risk of Breast Cancer
Affiliations of authors: S. Davis, Ph.D., Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle; D. K. Mirick, Program in Epidemiology, Fred Hutchinson Cancer Research Center; R. G. Stevens, Department of Community Medicine, University of Connecticut Health Center, Farmington.
Correspondence to: Scott Davis, Ph.D., Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North MP-474, P.O. Box 19024, Seattle, WA 981091024 (e-mail: sdavis@fhcrc.org).
Drs. Spiegel and Sephton rightly point out that the association we reported (1) between being employed in graveyard shift work and an increased risk of breast cancer might be accounted for by mechanisms other than or in addition to suppression of the normal nocturnal rise in melatonin, and they suggest that loss of diurnal variation in cortisol levels might be one such alternative. Women who engage in night shift work are subject to the influence
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