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JNCI Journal of the National Cancer Institute 2002 94(13):1030-1031; doi:10.1093/jnci/94.13.1030
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 13, 1030-1031, July 3, 2002
© 2002 Oxford University Press

CORRESPONDENCE

RESPONSE: Re: Cisplatin-Based Therapy for Elderly Patients With Advanced Non-Small-Cell Lung Cancer: Implications of Eastern Cooperative Oncology Group 5592, a Randomized Trial

Corey J. Langer, David H. Johnson

Affiliations of authors: C. J. Langer, Fox Chase Cancer Center, Philadelphia, PA; D. H. Johnson, Vanderbilt-Ingram Cancer Center, Nashville, TN.

Correspondence to: Corey J. Langer, M.D., Fox Chase Cancer Center, Department of Medical Oncology, 7701 Burholme Ave., Philadelphia, PA 19111 (e-mail: CJ_Langer@fccc.edu).

The first 10% of the full text of this article appears below.

We appreciate the comments of Perrone et al., who raise the specter of selection bias and, as evidence, cite the disproportionate underenrollment of elderly patients in the Eastern Cooperative Oncology Group (ECOG) 5592 trial (1) and in other efforts (2). They contend that oncologists preferentially recruit particularly well performing patients and that such individuals are not representative of the elderly population at large. Unfortunately, . . . [Full Text of this Article]


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