© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 13, 1029-1030,
July 3, 2002
© 2002 Oxford University Press
CORRESPONDENCE |
Re: Cisplatin-Based Therapy for Elderly Patients With Advanced Non-Small-Cell Lung Cancer: Implications of Eastern Cooperative Oncology Group 5592, a Randomized Trial
Affiliations of authors: F. Perrone, Clinical Trials Unit, National Cancer Institute (NCI), Naples, Italy; C. Gallo, Medical Statistics, Second University of Naples, Naples, Italy; C. Gridelli, Medical Oncology, S. Giuseppe Moscati Hospital, Avellino, Italy. All authors are members of the Clinical Trials Promoting Group (CTPG)–Lung Cancer Section.
Correspondence to: F. Perrone, M.D., Ph.D., Clinical Trials Unit, NCI, via M. Semmola, 80131 Naples, Italy (e-mail: fr.perrone@agora.it).
| The first 10% of the full text of this article appears below. |
A recent report by Langer et al. (1) in the Journal suggests that cisplatin-based therapy for treatment of advanced non-small-cell lung cancer (NSCLC) should not be denied to fit elderly patients. Their conclusion is based on a retrospective analysis of the Eastern Cooperative Oncology Group (ECOG) 5592 phase III randomized trial of three cisplatin-based regimens, which showed that outcomes did not differ between adult patients younger than 70 years of age and elderly patients 70 years of age
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