Skip Navigation

JNCI Journal of the National Cancer Institute 2001 93(8):645-647; doi:10.1093/jnci/93.8.645
© 2001 by Oxford University Press
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Hong, Y.-C.
Right arrow Articles by Christiani, D. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hong, Y.-C.
Right arrow Articles by Christiani, D. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of the National Cancer Institute, Vol. 93, No. 8, 645-647, April 18, 2001
© 2001 Oxford University Press

BRIEF COMMUNICATION

Maternal Genetic Effects on Neonatal Susceptibility to Oxidative Damage From Environmental Tobacco Smoke

Yun-Chul Hong, Heon Kim, Moon-Whan Im, Kwan-Hee Lee, Bok-Hi Woo, David C. Christiani

Affiliations of authors: Y.-C. Hong (Department of Occupational and Environmental Medicine), M.-W. Im (Department of Obstetrics and Gynecology), K.-H. Lee (Department of Preventive Medicine), Inha University College of Medicine, Inchon, Korea; H. Kim, Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea; B.-H. Woo, Department of Obstetrics and Gynecology, Ewha Women's University College of Medicine, Seoul, Korea; D. C. Christiani, Department of Environmental Health, Harvard School of Public Health, Boston, MA.

Correspondence to: Yun-Chul Hong, M.D., Ph.D., Department of Occupational and Environmental Medicine, Inha University College of Medicine, 7–206, 3-Ga Shinheung-Dong, Jung-Gu, Inchon, 400–103, South Korea (e-mail: ychong@inha.ac.kr).

Molecular epidemiologic studies (1,2) have demonstrated an association between environmental pollutants and in utero developmental damage. Among the environmental pollutants to which developing fetuses are reported to be vulnerable is environmental tobacco smoke (ETS) (3). ETS is a complex mixture of volatiles and particulate matter comprising numerous compounds, including polycyclic aromatic hydrocarbons (PAHs), which cause oxidative damage (4). Maternal ETS exposure has been found to be an important risk factor for reduced birth weight, small-for-gestational age, and premature delivery (5–8). Recently, biologic monitoring methods for the measurement of PAH exposure and the resulting oxidative injury have been used to evaluate the effects of environmental pollutant exposure (9,10). Sensitive biologic markers allow a more accurate quantification of PAH exposure levels and early biologic effects than external . . . [Full Text of this Article]

NOTES

REFERENCES


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?