© 2001 by Oxford University Press
Journal of the National Cancer Institute, Vol. 93, No. 22, 1753,
November 21, 2001
© 2001 Oxford University Press
CORRESPONDENCE |
Re: Tamoxifen and Contralateral Breast Cancer: the Other Side
Affiliation of authors: Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA.
Correspondence to: Christopher I. Li, M.D., M.P.H., Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Ave., N., MP 381, P.O. Box 19024, Seattle, WA 981091024 (e-mail: cili@fhcrc.org).
In her editorial (1) regarding our report (2) on the relationship between tamoxifen therapy for primary breast cancer and risk of contralateral breast cancer by estrogen receptor (ER) status, Dr. Swain comments that we "did not find a statistically significant reduction in contralateral breast cancer in women treated with adjuvant tamoxifen, with a hazard ratio [HR]) of 0.9 (95% confidence interval [CI] = 0.7 to 1.2). This negative finding seriously calls into question the
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