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JNCI Journal of the National Cancer Institute 2001 93(21):1585; doi:10.1093/jnci/93.21.1585-d
© 2001 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 93, No. 21, 1585, November 7, 2001
© 2001 Oxford University Press

MEMORANDUM FOR: Science Writers and Editors on the Journal Press List

Prophylactic Mastectomy Is Associated With Reduced Breast Cancer Risk in Known BRCA1 and BRCA2 Mutation Carriers

November 1, 2001 (EMBARGOED FOR RELEASE 4 P.M. ET November 6)

Katherine Arnold, Deputy News Editor, Dan Eckstein, (301) 986-1891, ext. 112

Prophylactic removal of both breasts is associated with a reduced risk of a subsequent breast cancer by 89.5% to 100% among women who carry cancer-related BRCA1 or BRCA2 mutations.

Lynn Hartmann, M.D., at the Mayo Clinic, Rochester, Minn., and associates, identified 26 women with BRCA1 or BRCA2 alterations among a group of 214 high-risk women who had prophylactic mastectomies. None of these 26 women has developed breast . . . [Full Text of this Article]


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