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JNCI Journal of the National Cancer Institute 2001 93(16):1264-1266; doi:10.1093/jnci/93.16.1264
© 2001 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 93, No. 16, 1264-1266, August 15, 2001
© 2001 Oxford University Press

BRIEF COMMUNICATION

Effect of Age on Risk of Second Primary Colorectal Cancer

Imad Shureiqi, Catherine D. Cooksley, Jeffrey Morris, Amr S. Soliman, Bernard Levin, Scott M. Lippman

Affiliations of authors: I. Shureiqi (Departments of Clinical Cancer Prevention and Gastrointestinal Medical Oncology), C. D. Cooksley (Department of Health Services Research), J. Morris (Department of Biostatistics), A. S. Soliman (Department of Epidemiology), B. Levin (Division of Cancer Prevention), S. M. Lippman (Department of Clinical Cancer Prevention), The University of Texas M. D. Anderson Cancer Center, Houston.

Correspondence to: Scott M. Lippman, M.D., Department of Clinical Cancer Prevention, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Box 236, Houston, TX 77030–4095 (e-mail: slippman@mdanderson.org).

Patients with a history of colorectal cancer are considered to be at a high risk of colorectal second primary tumors (SPTs), for which they usually receive intensive surveillance (1–3). Actual data on risk of SPTs (all from retrospective analyses) are not consistent, however, and even when increased relative to the risk of a first colorectal cancer in the general population, the risk of an SPT was modest (4–9). Reported incidences of colorectal SPTs also vary widely, ranging from 0.3% to 3.6% (based on variable mean follow-ups ranging from approximately 3 to >10 years) (4–10). Limited data suggest that the risk of a colorectal SPT is higher in younger than in older patients (4,6). A better understanding of the risk faced by patients with a history of colorectal cancer will help to determine whether all . . . [Full Text of this Article]

NOTES

REFERENCES


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