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JNCI Journal of the National Cancer Institute 2000 92(23):1947; doi:10.1093/jnci/92.23.1947
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 23, 1947, December 6, 2000
© 2000 Oxford University Press

CORRESPONDENCE

Re: Population-Based, Case–Control Study of HER2 Genetic Polymorphism and Breast Cancer Risk

Margaret-Mary Ameyaw, Nadia Thornton, Howard L. McLeod

Affiliation of authors: Department of Medicine and Therapeutics, Institute of Medical Sciences, Foresterhill, Aberdeen, U.K.

Correspondence to present address: Howard L. McLeod, D.Pharm., Department of Medicine, Division of Oncology, Washington University Medical School, Rm. 1021 CSRB NT, 660 S. Euclid Ave., Campus Box 8069, St. Louis, MO 63110–1093 (e-mail: hmcleod@imgate.wustl.edu).

Altered expression of the protooncogene HER2 (also known as c-erbB-2) gene has been implicated in the carcinogenesis and prognosis of breast cancer and other solid tumors (1,2). It is also a cancer therapeutic target, with antibody-based therapy against the Her2 protein, and a predictive marker . . . [Full Text of this Article]

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