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JNCI Journal of the National Cancer Institute 2000 92(2):161-162; doi:10.1093/jnci/92.2.161
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 2, 161-162, January 19, 2000
© 2000 Oxford University Press

CORRESPONDENCE

More About: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma

Stephen B. Fox, Kevin C. Gatter, Russel D. Leek, Adrian L. Harris, Karen L. Chew, Brian H. Mayall, Dan H. Moore, II

Affiliations of authors: S. B. Fox, K. C. Gatter (Department of Cellular Science), R. D. Leek, A. L. Harris (Molecular Oncology), Imperial Cancer Research Fund, University of Oxford, John Radcliffe Hospital, Oxford, U. K.; K. L. Chew, B. H. Mayall, Department of Laboratory Medicine and the Cancer Center, University of California, San Francisco, CA; D. H. Moore II, Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco.

Correspondence to: Stephen B. Fox, M.D., Anatomical Pathology, Canterbury Health, Christchurch Hospital, Christchurch, New Zealand (e-mail: sfox@chmeds.ac.nz).

Axelsson et al. (1) reported in this Journal that microvessel density (MVD) in 220 breast cancers did not provide prognostic information for metastasis-free or overall survival; this result was contrary to most published series (2). The study was designed to assess the reliability of MVD to predict the outcome for patients with breast cancer. MVD was measured by two observers who independently selected and scored the three most vascular fields. The maximum . . . [Full Text of this Article]

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