© 1999 by Oxford University Press
Journal of the National Cancer Institute, Vol. 91, No. 20, 1719-1724,
October 20, 1999
© 1999 Oxford University Press
COMMENTARY |
Prostate Cancer Practice Patterns and Quality of Life: the Prostate Cancer Outcomes Study
Affiliations of authors: A. L. Potosky, L. C. Harlan, J. Legler, Applied Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD; J. L. Stanford, Fred Hutchinson Cancer Research Center, Seattle, WA; F. D. Gilliland, New Mexico Tumor Registry, Albuquerque, and University of Southern California School of Medicine, Department of Preventive Medicine, Los Angeles; A. S. Hamilton, D. Deapen, University of Southern California School of Medicine, Department of Preventive Medicine, Los Angeles; P. C. Albertsen, Division of Urology, University of Connecticut Health Center, Farmington; J. W. Eley, J. M. Liff, Georgia Center for Cancer Statistics, Rollins School of Public Health, Emory University, Atlanta; R. A. Stephenson, Division of Urology, University of Utah Department of Medicine, Salt Lake City; C. E. Ferrans, The University of Illinois at Chicago, College of Nursing; J. A. Talcott, Massachusetts General Hospital, Department of General Internal Medicine, Boston; M. S. Litwin, Departments of Urology and Health Services, Schools of Medicine and Public Health, University of California at Los Angeles.
Correspondence to: Arnold L. Potosky, Ph.D., National Institutes of Health, EPN, Rm. 313, 6130 Executive Blvd. MSC 7344, Bethesda, MD 20892-7344 (overnight mail: Rockville, MD 20852) (e-mail: potosky@nih.gov).
| INTRODUCTION |
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Prostate cancer is the most commonly diagnosed (non-skin) cancer among men in the United States, with 179 000 new cases and 37 000 deaths expected in 1999 (1). Although $5 billion is spent annually for the care of those diagnosed with prostate cancer (2), a systematic evaluation of practice patterns and the impact of treatments on health-related quality of life (HRQOL) on a national scale has yet to be conducted. In 1994, the National Cancer Institute (NCI) initiated the Prostate Cancer Outcomes Study (PCOS) to investigate variations in the initial treatment of prostate cancer and to describe HRQOL outcomes in a large, heterogeneous cohort of newly diagnosed prostate cancer patients treated in community medical practices. The study is the most comprehensive population-based outcomes study focusing on prostate cancer ever conducted and complements the national prostate cancer research agenda.
The main purpose of this commentary is to
| BACKGROUND AND OBJECTIVES |
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| METHODS |
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PCOS Sample Design
HRQOL Survey
Medical Record Abstraction
Statistical Methods
| RESULTS |
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Response to the PCOS
Representativeness
| COMMENT |
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| APPENDIX: DISEASE-SPECIFIC INDEX (All items refer to "over the past month.") |
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| NOTES |
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| REFERENCES |
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