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JNCI Journal of the National Cancer Institute 1999 91(1):10-12; doi:10.1093/jnci/91.1.10
© 1999 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 91, No. 1, 10-12, January 6, 1999
© 1999 Oxford University Press

NEWS

Randomized Controlled Trials Mark a Golden Anniversary

Judith Randal

It would be hard to think of anything more central to medical progress than the knowledge made possible by randomized controlled trials. Today's physicians in virtually every specialty —oncology emphatically included — pay close attention to the results of those trials, and tomorrow's doctors surely will too. So why were there no RCTs until after World War II? And what did it take to make them a reality?

A good place to get answers to these questions was provided in London last October when the British Medical Journal held a 2-day international conference to commemorate the 50th anniversary of the appearance in the BMJ on Oct. 30, 1948, of "Streptomycin Treatment of Pulmonary Tuberculosis."

The first RCT to be completed and, therefore, the first to be published, it was run by England's Medical Research Council and pitted streptomycin and bed rest against bed . . . [Full Text of this Article]

Rigid Controls

"Me Too" Drugs


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