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Journal of the National Cancer Institute Advance Access originally published online on November 16, 2009
JNCI Journal of the National Cancer Institute 2009 101(22):1525-1526; doi:10.1093/jnci/djp385
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© The Author 2009. Published by Oxford University Press. All rights reserved.

EDITORIALS

Cigarette Smoking and Bladder Cancer: A New Twist in an Old Saga?

Anthony J. Alberg, James R. Hébert

Affiliations of authors: Hollings Cancer Center and Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, Charleston, SC (AJA); Cancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC (JRH)

Correspondence to: Anthony J. Alberg, PhD, MPH, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, PO Box 250955, Charleston, SC 29425 (e-mail: alberg@musc.edu).

The first 10% of the full text of this article appears below.

Cigarette smoking was first evaluated as a risk factor for bladder cancer more than 50 years ago (1). As early as 1964, the Surgeon General's report summarized results from four case–control studies and seven prospective cohort studies. In the case–control studies, the odds ratios in men ranged from 2.0 to 3.3 (2). In the cohort studies, the mean relative risk of bladder cancer mortality in smokers, relative to nonsmokers, was 1.9 (2). The data suggested that the association of smoking with bladder cancer increased according to smoking frequency and depth of inhalation. This evidence led to the conclusion that " ... available data suggest an association between cigarette smoking and urinary bladder . . . [Full Text of this Article]

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J Natl Cancer Inst 2009 101: 1523. [Extract] [Full Text] [PDF]

Erratum:
J Natl Cancer Inst 2010 102: 138. [Extract] [Full Text] [PDF]