Journal of the National Cancer Institute Advance Access originally published online on February 26, 2008
JNCI Journal of the National Cancer Institute 2008 100(5):298-299; doi:10.1093/jnci/djn050
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© Oxford University Press 2008.
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Fat May Fuel Breast Cancer Growth
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Maintaining a healthy weight and exercising regularly have become standard advice for lowering the risk of breast cancer. But researchers are finding that these lifestyle changes may also be associated with better survival and lower recurrence in women with breast cancer.
New evidence from several fronts suggests that excess body fat promotes breast cancer growth and that reducing body fat and increasing physical activity improve the odds of survival. Results of the Million Woman Study, a longitudinal cohort study of 1.2 million women in the U.K., concluded that being overweight or obese is associated with a higher risk of postmenopausal breast cancer and lower survival. The report, published in December in the British Medical Journal, also found an association between high body mass index and other cancers, such as endometrial cancer and cancer of the esophagus.
That report, along with several other large prospective studies, should put to
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