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Journal of the National Cancer Institute Advance Access originally published online on January 29, 2008
JNCI Journal of the National Cancer Institute 2008 100(3):225; doi:10.1093/jnci/djm303
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© The Author 2008. Published by Oxford University Press.

CORRESPONDENCE

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Janelle M. Hoskins, Howard L. Mcleod

Affiliation of authors: Division of Pharmacotherapy and Experimental Therapeutics and the Lineberger Comprehensive Cancer Center, UNC Institute for Pharmacogenomics and Individualized Therapy, University of North Carolina, Chapel Hill, NC

Correspondence to: Howard L. McLeod, PharmD, UNC Institute for Pharmacogenomics and Individualized Therapy, University of North Carolina, Chapel Hill, Campus Box 7360, Kerr Hall, Chapel Hill, 27599-7360 NC (e-mail: hmcleod@unc.edu).

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We thank Dr Ichikawa and colleagues for their kind comments. Their preliminary irinotecan pharmacokinetic data from Japanese cancer patients with low-activity UGT1A1 genotypes who participated in an irinotecan dose escalation . . . [Full Text of this Article]


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Related Correspondence

Re: UGT1A1*28 Genotype and Irinotecan-Induced Neutropenia: Dose Matters
Wataru Ichikawa, Kazuhiro Araki, Ken-Ichi Fujita, Wataru Yamamoto, Hisashi Endo, Fumio Nagashima, Ryuhei Tanaka, Toshimichi Miya, Keiji Kodama, Yu Sunakawa, Masaru Narabayashi, Yuichi Ando, Yuko Akiyama, Kaori Kawara, and Yasutsuna Sasaki
J Natl Cancer Inst 2008 100: 224-225. [Extract] [Full Text] [PDF]