Journal of the National Cancer Institute Advance Access originally published online on July 29, 2008
JNCI Journal of the National Cancer Institute 2008 100(15):1052-1054; doi:10.1093/jnci/djn284
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© Oxford University Press 2008.
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Possible MRI–Mastectomy Link Sparks Debate on MRI's Role in Breast Cancer Management
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After years of decline, the number of breast cancer patients choosing mastectomy over breast-conserving surgery is on the rise, and a new study suggests that the use of highly sensitive magnetic resonance imaging (MRI) may be at least partly responsible.
The study raises questions about the appropriate use of MRI in making treatment decisions about breast cancer and whether the technology should be offered to early-stage, low-risk breast cancer patients.
"Sometimes our technologies get ahead of our evidence-based medicine," said Matthew Goetz, M.D., a medical oncologist at the Mayo Clinic and lead investigator of the study, which looked at surgical outcomes of all early-stage breast cancer patients seen at Mayo Clinic's Rochester, Minn., hospital from 1997 to 2006. In the retrospective study, presented at the American Society for Clinical Oncology meeting in May, the research team found an association between mastectomy rates and preoperative MRI. The researchers controlled for
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J Natl Cancer Inst 1994 86: 1202-1208.
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