Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome
J. Natl. Cancer Inst. Winnepenninckx et al.
98: 472
Supplementary Tables
The following supplementary tables accompany this Article:
Files in this Data Supplement:
- Supplementary Table 1 -
List of 361 sequences discriminating between melanomas associated with distant metastasis free-survival (DMFS) of less than or equal to 4 years or more than 4 years (adjusted P<.05; any adjusted P value less than .05 was considered statistically significant). Raw_p = nonadjusted P value for t test comparing the average expressions between the two groups; fdr_p = P value adjusted for the false discovery rate; mean0 = average log ratio of the expressions of the primary tumors in the good prognosis group (M–), compared with the reference pool; std0 = standard deviation of these log ratio values; mean1 = average log ratio of the expressions of the primary tumors in the poor prognosis group (M+), compared with to the reference pool; std1 = standard deviation of these log ratio values; Agilent_accession: Agilent accession number; probe = Agilent oligonucleotide reference; accession = gene code in the data base (LocusLink,GeneBank); gene_symbol = gene symbol in LocusLink database; description = gene description in LocusLink database; location = gene chromosomal location in LocusLink database. All statistical tests were two-sided.
- Supplementary Table 2 -
Correlation between sequences and thickness (adjusted P<.05). Correl = Pearson correlation value between the log ratio of the primary tumors expressions, compared with the reference pool and the corresponding thicknesses; raw_p = nonadjusted P value for test of significance of the Pearson correlation value; fdr_p = P value adjusted for the false discovery rate; Agilent_accession: Agilent accession number; probe = Agilent oligonucleotide reference; accession = gene code in the data base (LocusLink,GeneBank); gene_symbol = gene symbol in LocusLink database; description = gene description in LocusLink database; location = gene chromosomal location in LocusLink database. All statistical tests were two-sided.
- Supplementary Table 3 -
List of 254 sequences discriminating between melanomas associated with distant metastasis free-survival (DMFS) of less than or equal to 4 years or more than 4 years used in the prediction rule. Order = order of importance as determined by P value; Agilent_accession: Agilent accession number; accession = gene code in the data base (LocusLink,GeneBank); gene_symbol = gene symbol in LocusLink database; direction = relative expression in melanomas in group M+ vs. group M–, as shown by the oligonucleotide microarray data; involvement in melanoma = references from PubMed publications; involvement in non-melanoma cancer = type of cancer and references from PubMed publications.
