Use of Three-Dimensional Tissue Cultures to Model Extravascular Transport and Predict In Vivo Activity of Hypoxia-Targeted Anticancer Drugs
J. Natl. Cancer Inst. Hicks et al.
98: 1118
Supplementary Data
The following supplementary data accompanies this article:
Files in this Data Supplement:
- Supplementary Data -
Includes further detail of materials and methods, supplemental figures 1 and 2, supplemental tables 1-3 and additional references.
- GreensTPZ03.zip
-
A downloadable FORTRAN version of the Green's function program for simulating oxygen and drug transport in the three dimensional tumor microregion. Please note, Oxford University Press, The Journal of the National Cancer Institute and the authors take no responsibility for any side effects this program may have on a user's computer. No assurance is given that it is free of errors and any use is at the user's risk. A FORTRAN compiler will be required to compile the programs. Unzip to a suitable location such as D:\greens. Instructions can be found in the MS word document: Readme.doc. These are instructions for compiling and running the program only. See the manuscript and supporting information for more detail on the theory. Program updates may be found at: http://www.health.auckland.ac.nz/cancer/cv/hicks.htm or http://www.physiology.arizona.edu/people/secomb/index.html.
