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Correction for Garber, J. Natl. Cancer Inst. 97 (3) 166-167.
JNCI Journal of the National Cancer Institute 2005 97(6):418; doi:10.1093/jnci/97.6.418-b
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© 2005 Oxford University Press

NEWS

Clarification

A News story in the February 2 issue of the Journal ("Missing the Target: Ubiquitin Ligase Drugs Stall," Vol. 97, No. 3, p. 166) omitted the context of the Nobel Prize–winning accomplishments of Avram Hershko, M.D., Ph.D., and Aaron Ciechanover, M.D., D.Sc., failing to mention their key experimental and extensive conceptual work done between 1978 and 1983. Attacking an obscure problem, ATP-dependent proteolysis, Hershko and Ciechanover, partially in collaboration with Irwin A. Rose, Ph.D., elucidated all the major elements of the ubiquitin–proteasome system and their basic cellular role in proteolysis, now recognized as fundamental to biology. A more detailed explanation of their work was reported in the Journal in 2002 (Vol. 94, No. 8, p. 550).


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