Cellular Retinol-Binding Protein I, a Regulator of Breast Epithelial Retinoic Acid Receptor Activity, Cell Differentiation, and Tumorigenicity
J. Natl. Cancer Inst. Farias et al.
97: 21
Supplementary Figure
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Phase contrast micrographs depicting the morphology of representative 10-day-old three-dimensional Matrigel outgrowths. A) Sarcoma virus 40–immortalized mammary epithelial cell lines (MTSV1-7) transfected with vector, wild type (WT) cellular retinol-binding protein-I (CRBP-I), leucine to alanine at amino acid (aa) 29 (L29A) mutant CRBP-I, or arginine to glutamate at aa 58 (R58E) mutant CRBP-I. B) MTSVCRBP-I cells were stably transfected with empty vector (Control) or lecithin retinol acyltransferase mutant (LRAT C161A). Scale bar = μm.