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Table 2. Risk ratio of invasive breast cancer*
Risk ratio 95% CI

Placebo
Tamoxifen

NSABP P-1 (14) All 175 89 0.51 0.39 to 0.66
ER+ 130 41 0.31 0.22 to 0.45
ER- 31 38 1.22 0.74 to 2.03

Placebo
Raloxifene

MORE (15) (invasive) 27 13 0.24 0.13 to 0.44
ER+ 20 4 0.10 0.04 to 0.24
ER- 4 7 0.88 0.26 to 3.00

*CI = confidence interval; NSABP = National Surgical Adjuvant Breast and Bowel Project; ER = estrogen receptor; MORE = Multiple Outcomes of Raloxifene Evaluation.





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